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Taking aim at the dreaded tropical disease leishmaniasis

Leishmania is a microorganism threatening the health of over 500 million people at risk of crossing its path. Although leishmaniasis, the disease caused by the parasite, has been on the radar of scientists for a long time, the quest for affordable and effective treatment continues. Researchers have now developed a new, cost-effective strategy to rapidly identify molecules capable of eliminating Leishmania.

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Signaling cascade that repairs damaged nerve cells characterized

Through a study of roundworm nerve cells with severed axons, researchers showed that a signaling cascade that normally functions in promoting the phagocytosis of apoptotic cells also acts in inducing axon regeneration. The findings shed light on a fundamental feature of nerve repair, which is limited in the central nervous system in humans, and thus could pave the way towards treatments for brain and spinal cord injuries.

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