New epigenetic drug strategy to treat cancer
Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer. Reactivation leads to restored tumor suppressor gen..
Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer. Reactivation leads to restored tumor suppressor gen..
Scientists have discovered how the growth of milk-producing mammary glands is triggered during puberty. Sleeping stem cells in the mammary gland are awoken by a protein dubbed FoxP1, according to the ..
Scientists have elucidated the three-dimensional structure of an assembly of proteins operating on cells that dampen immune responses. They also discovered how an antibody can block this assembly and ..
An innovative filtering material may soon reduce the environmental cost of manufacturing plastic. The material, a metal-organic framework, can extract ethylene, the key ingredient in the most common f..
New study finds that experimental drug sparsentan is an effective treatment for the rare kidney disease focal segmental glomerulosclerosis, which currently has no FDA-approved therapies.
Coral reefs are envisioned as the seats of great biodiversity, but they may not be where all that diversity got its start. Paleobiologists reveal that the earliest fish may have diversified in shallow..
New research suggests that 30 years after the first epidemiological survey of the seroprevalence of Human T-cell lymphotropic virus type 1 (HTLV-1) infections in Gabon, the country remains highly ende..
Endometriosis — a condition caused by uterine tissue growing outside of the organ — affects 10 percent of reproductive-aged women, whom it causes chronic pain that is significant and debilitating. N..
An examination into the detection of harbour porpoises is helping to give new understanding of effective monitoring of species under threat from anthropogenic activities such as fisheries bycatch and ..
The first study investigating the mechanism of how a disease develops using human organ-on-a-chip technology has been successfully completed by engineers.