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New assay to detect genetic abnormalities in sarcomas outperforms conventional techniques

A report describes a new assay, anchored multiplex PCR (AMP)-based targeted next-generation-sequencing (NGS), with superior diagnostic utility compared to conventional techniques. This includes the ability to analyze numerous target genes simultaneously and identify new fusion partners. In four cases, the assay diagnosed sarcoma in samples deemed falsely negative by conventional tests.

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Autonomous gene expression control nanodevice will contribute to medical care

Researchers constructed integrated gene logic-chips called 'gene nanochips.' These self-contained nanochips can switch genes on or off according to the environment, where photo-reprogramming of the logic operation by UV irradiation is possible. Moreover, the researchers completed proof-of-concept experiments using artificial cells that produced the diagnostics and reactants (the desired RNA and protein) in a confined nanochip, suggesting the potential of autonomous nanochips in future medical prevention and care.

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Next-gen insect repellents to combat mosquito-borne diseases

Nearly 700 million people suffer from mosquito-borne diseases — such as malaria, West Nile, Zika and dengue fever — each year, resulting in more than 1 million deaths. Today, researchers report a new class of mosquito repellents based on naturally occurring compounds that are effective in repelling the bugs, including those that are resistant to pyrethroid insecticides and repellents.

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