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Chemical engineers uncover ways to pattern solid surfaces to enhance how water interacts with them

The dynamics of water near solid surfaces play a critical role in numerous technologies, including water filtration and purification, chromatography and catalysis. One well-known way to influence those dynamics, which in turn affects how water “wets” a surface, is to modify the surface hydrophobicity, or the extent to which the surface repels water. Such modifications can be achieved by altering the average coverage, or surface density, of hydrophobic chemical groups on the interface.

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STAT3 can be a therapeutic target for chronic active EBV infection, a fatal disorder

Chronic active Epstein-Barr virus infection (CAEBV) is an inflammatory disorder with potential for tumor development. Here, unusual phosphorylation was observed on STAT3 in EBV-infected T- or NK-cells from patients with CAEBV. Researchers found that ruxolitinib, a drug that is currently used for treatment of myelofibrosis and polycythemia vera, could suppress the survival of these EBV-infected cells in a dose-dependent manner, and that STAT3 could be an important new target for treatment of CAEBV.

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