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Found: A destructive mechanism that blocks the brain from knowing when to stop eating

Researchers have uncovered a destructive mechanism at the molecular level that causes a well-known phenomenon associated with obesity: leptin resistance. They found that mice fed a high-fat diet produce an enzyme named MMP-2 that clips receptors for the hormone leptin from the surface of neuronal cells in the hypothalamus. This blocks leptin from binding to its receptors. This in turn keeps the neurons from signaling that your stomach is full and you should stop eating.

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Microsoft: Office 365 for Mac subscribers must run newer editions of macOS

Microsoft has warned Mac subscribers of Office 365 that they must be running either macOS Sierra or macOS High Sierra next month when the company updates the productivity applications.
“As of the Office 365 for Mac September 2018 update, macOS 10.12 or later is required to update to the new version of the Office client apps for Mac and receive new feature updates,” Microsoft announced in a support document.
Microsoft will probably deliver the Office 365 September update around September 11 or 12 if it sticks to the usual monthly refresh schedule.
To read this article in full, please click here

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news

Microsoft: Office 365 for Mac subscribers must run newer editions of macOS

Microsoft has warned Mac subscribers of Office 365 that they must be running either macOS Sierra or macOS High Sierra next month when the company updates the productivity applications.
“As of the Office 365 for Mac September 2018 update, macOS 10.12 or later is required to update to the new version of the Office client apps for Mac and receive new feature updates,” Microsoft announced in a support document.
Microsoft will probably deliver the Office 365 September update around September 11 or 12 if it sticks to the usual monthly refresh schedule.
To read this article in full, please click here

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