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How do fruit flies grow legs? Solving a molecular mystery

What do cancer and the growing legs of a fruit fly have in common? They can both be influenced by a single molecule, a protein that tends to call the shots. Present in virtually every creature on the planet, this protein goes by the name Epidermal Growth Factor Receptor protein, or EGFR. Now a team of neuroscientists has figured out how to tease apart the many roles EGFR plays in the body — challenging conventional wisdom in the process.

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Reversing influences of intergenerational stress offers hope for addressing public health

Researchers have shown for the first time in an animal model it is possible to reverse influences of parental stress by exposing parents to behavioral interventions following their own exposure to stress. This study has important public health implications for preventing future generations from bearing influences of stressors their parents faced before the children were conceived.

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HIV RNA expression inhibitors may restore immune function in HIV-infected individuals

Immune activation and inflammation persist in the majority of treated HIV-infected individuals and is associated with excess risk of mortality and morbidity. A new study suggests that use of HIV RNA expression inhibitors as adjunct therapy might diminish atypical inflammation and restore immune function in HIV-infected individuals on combination antiretroviral therapy (cART).

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Water vapor annealing technique on diamond surfaces for next-generation power devices

The existing surface termination technique using hydrogen to stabilize the diamond's structure for application in electronic power devices results in two-dimensional hole gas layers (2DHG). Attempting to remove these layers using oxygen-termination roughens the diamond surface and leads to degradation of the device performance. To overcome this, researchers removed 2DHG from diamond using water vapor annealing and maintained an atomically flat surface.

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