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Novel role of protein in important pathways that lead to cancer malignancy

Researchers have revealed for the first time that a specific protein, the fatty acid-binding protein 5 (FABP5), plays a critical role in the development and metastasis of highly aggressive prostate and breast cancer cells. They point out that a better understanding of the molecular pathways of specific cancers is a step in the direction of finding more effective therapeutic targets.

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Genetically encoded sensor tracks changes in oxygen levels with very high sensitivity

Based on a protein from E. coli, scientists have developed a fluorescent protein sensor able to provide real-time information on dynamic changes in oxygen levels with very high sensitivity. As the oxygen level is a major determinant of cellular function, the idea behind this sensor may revolutionize our ability to detect cellular changes of critical importance, such as in tumors and following stroke and heart attack.

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